Friday, September 30, 2016

Phenylephrine/Pyrilamine/Dextromethorphan Drops


Pronunciation: fen-ill-EF-rin/peer-IL-a-meen /dex -troe-meth-OR-fan
Generic Name: Phenylephrine/Pyrilamine/Dextromethorphan
Brand Name: Examples include Albatussin Pediatric NR and Poly Hist DM


Phenylephrine/Pyrilamine/Dextromethorphan Drops are used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.


Phenylephrine/Pyrilamine/Dextromethorphan Drops are a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.


Do NOT use Phenylephrine/Pyrilamine/Dextromethorphan Drops if:


  • you are allergic to any ingredient in Phenylephrine/Pyrilamine/Dextromethorphan Drops

  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems

  • you are unable to urinate or are having an asthma attack

  • you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Phenylephrine/Pyrilamine/Dextromethorphan Drops:


Some medical conditions may interact with Phenylephrine/Pyrilamine/Dextromethorphan Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat; heart blood vessel problems; or other heart problems

  • if you have a history of adrenal gland problems (eg, adrenal gland tumor); high blood pressure; diabetes; stroke; glaucoma; a blockage of your stomach, bladder, or intestines; ulcers; trouble urinating; enlarged prostate; seizures; or an overactive thyroid

  • if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Phenylephrine/Pyrilamine/Dextromethorphan Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Phenylephrine/Pyrilamine/Dextromethorphan Drops may be increased

  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased

  • Bromocriptine or hydantoins (eg, phenytoin) because side effects may be increased by Phenylephrine/Pyrilamine/Dextromethorphan Drops

  • Guanadrel, guanethidine, methyldopa, mecamylamine, or reserpine because effectiveness may be decreased by Phenylephrine/Pyrilamine/Dextromethorphan Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Phenylephrine/Pyrilamine/Dextromethorphan Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Phenylephrine/Pyrilamine/Dextromethorphan Drops:


Use Phenylephrine/Pyrilamine/Dextromethorphan Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Phenylephrine/Pyrilamine/Dextromethorphan Drops may be taken with or without food.

  • Use the dropper that comes with Phenylephrine/Pyrilamine/Dextromethorphan Drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of Phenylephrine/Pyrilamine/Dextromethorphan Drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Phenylephrine/Pyrilamine/Dextromethorphan Drops.



Important safety information:


  • Phenylephrine/Pyrilamine/Dextromethorphan Drops may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Phenylephrine/Pyrilamine/Dextromethorphan Drops. Using Phenylephrine/Pyrilamine/Dextromethorphan Drops alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do not take diet or appetite control medicines while you are taking Phenylephrine/Pyrilamine/Dextromethorphan Drops without checking with your doctor.

  • Phenylephrine/Pyrilamine/Dextromethorphan Drops contains phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.

  • Do NOT exceed the recommended dose or take Phenylephrine/Pyrilamine/Dextromethorphan Drops for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Phenylephrine/Pyrilamine/Dextromethorphan Drops may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Phenylephrine/Pyrilamine/Dextromethorphan Drops. Use a sunscreen or protective clothing if you must be outside for a prolonged period.

  • If you are scheduled for allergy skin testing, do not take Phenylephrine/Pyrilamine/Dextromethorphan Drops for several days before the test because it may decrease your response to the skin tests.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Phenylephrine/Pyrilamine/Dextromethorphan Drops.

  • Use Phenylephrine/Pyrilamine/Dextromethorphan Drops with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Phenylephrine/Pyrilamine/Dextromethorphan Drops in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Phenylephrine/Pyrilamine/Dextromethorphan Drops, discuss with your doctor the benefits and risks of using Phenylephrine/Pyrilamine/Dextromethorphan Drops during pregnancy. It is unknown if Phenylephrine/Pyrilamine/Dextromethorphan Drops are excreted in breast milk. Do not breast-feed while taking Phenylephrine/Pyrilamine/Dextromethorphan Drops.


Possible side effects of Phenylephrine/Pyrilamine/Dextromethorphan Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Phenylephrine/Pyrilamine/Dextromethorphan side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of Phenylephrine/Pyrilamine/Dextromethorphan Drops:

Store Phenylephrine/Pyrilamine/Dextromethorphan Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Phenylephrine/Pyrilamine/Dextromethorphan Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Phenylephrine/Pyrilamine/Dextromethorphan Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Phenylephrine/Pyrilamine/Dextromethorphan Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Phenylephrine/Pyrilamine/Dextromethorphan Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Phenylephrine/Pyrilamine/Dextromethorphan resources


  • Phenylephrine/Pyrilamine/Dextromethorphan Side Effects (in more detail)
  • Phenylephrine/Pyrilamine/Dextromethorphan Use in Pregnancy & Breastfeeding
  • Phenylephrine/Pyrilamine/Dextromethorphan Drug Interactions
  • Phenylephrine/Pyrilamine/Dextromethorphan Support Group
  • 2 Reviews for Phenylephrine/Pyrilamine/Dextromethorphan - Add your own review/rating


Compare Phenylephrine/Pyrilamine/Dextromethorphan with other medications


  • Cold Symptoms
  • Hay Fever
  • Sinusitis

Proctocream HC


Generic Name: hydrocortisone and pramoxine topical (HYE droe KOR ti sone and pra MOX een)

Brand Names: Analpram E, Analpram-HC, Epifoam, HC Pramoxine, Hydropram, Novacort, Pramosone, Proctofoam HC, Rectocort HC, ZyPram


What is Proctocream HC (hydrocortisone and pramoxine topical)?

Pramoxine is an anesthetic. It works by interfering with pain signals sent from the nerves to the brain.


Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.


The combination of hydrocortisone and pramoxine topical is used to treat pain, itching, or inflammation of the skin caused by a number of conditions such as allergic reactions, eczema, psoriasis, insect bites, and minor burns or scrapes. This medication is also used on the rectal area to treat itching and inflammation caused by hemorrhoids, anal fissures, or other rectal irritation.


Hydrocortisone and pramoxine topical may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Proctocream HC (hydrocortisone and pramoxine topical)?


You should not use this medication if you are allergic to hydrocortisone or pramoxine, or if you have chickenpox or measles.

Before using hydrocortisone and pramoxine topical, tell your doctor if you are allergic to any drugs or any other anesthetics or "numbing medicines."


Hydrocortisone and pramoxine topical will not treat a bacterial, fungal, or viral skin infection. If you have a skin infection, you should not use this medication until your infection is treated and clears up.


Avoid using this medication on your face, near your eyes, or on body areas where you have skin folds or thin skin.


Do not use this medication on a child without a doctor's advice. Children are more sensitive to the effects of topical hydrocortisone. Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with hydrocortisone topical can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions. Contact your doctor if your condition does not improve or if it gets worse after using this medication for several days.

Do not use hydrocortisone and pramoxine topical for any condition that has not been checked by a doctor.


What should I discuss with my health care provider before using Proctocream HC (hydrocortisone and pramoxine topical)?


You should not use this medication if you are allergic to hydrocortisone or pramoxine, or if you have chickenpox or measles.

Before using hydrocortisone and pramoxine topical, tell your doctor if you are allergic to any drugs or any other anesthetics or "numbing medicines." Also tell your doctor if you have:



  • liver disease;




  • diabetes;




  • problems with your eyes;




  • a stomach or intestinal disorder;




  • a rectal sore or infection; or




  • if you use any drugs that weaken the immune system, including steroids.



Hydrocortisone and pramoxine topical will not treat a bacterial, fungal, or viral skin infection. If you have a skin infection, you should not use this medication until your infection is treated and clears up.


FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before using hydrocortisone and pramoxine topical, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether hydrocortisone and pramoxine topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child without a doctor's advice. Children are more sensitive to the effects of topical hydrocortisone.

How should I use Proctocream HC (hydrocortisone and pramoxine topical)?


Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.


Hydrocortisone and pramoxine topical is usually applied 3 or more times daily, depending on which form of this medication you use. Follow the label directions or your doctor's instructions about how much of this medication to use and how often. Do not use hydrocortisone and pramoxine topical for any condition that has not been checked by a doctor.


Wash your hands before and after applying this medication, unless you are using hydrocortisone and pramoxine topical to treat a hand condition.

When using this medication on the skin, apply just enough of the medication to cover the area to be treated. Rub in gently.


Avoid using this medication on your face, near your eyes or mouth, or on body areas where you have skin folds or thin skin.


Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with hydrocortisone topical can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions.

Before apply the rectal form of this medication (cream, lotion, or foam), clean the rectal area with mild soap and pat dry.


Use only a small amount of medicine when applying hydrocortisone and pramoxine around the outside of the rectum. You may first place the medicine onto a clean tissue and then wipe it gently onto your rectum.


When using this medication inside the rectum, insert only the applicator tip of the medicine tube or foam can into the anus, no deeper than 1 inch.


Shake the hydrocortisone and pramoxine rectal foam before each use. Contact your doctor if your condition does not improve or if it gets worse after using this medication for several days, or if your condition clears up and then comes back. Do not stop using hydrocortisone and pramoxine topical suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when you stop using the medication. Store this medication at room temperature away from moisture and heat. Keep the rectal foam canister away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty canister.

What happens if I miss a dose?


Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

An overdose of hydrocortisone and pramoxine topical is not expected to produce life-threatening symptoms. However, long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


What should I avoid while using Proctocream HC (hydrocortisone and pramoxine topical)?


Avoid using this medication on your face, near your eyes, or on body areas where you have skin folds or thin skin. If it does get into any of these areas, wash with water. Do not use hydrocortisone and pramoxine topical on deep skin wounds, blistered skin, severe burns, irritated skin, or large skin areas. Also avoid using this medication in open wounds.

Avoid applying other skin medications on the same treatment area with hydrocortisone and pramoxine topical, unless your doctor has told you to.


Using a steroid can lower the blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medicines.


Hydrocortisone pramoxine topical side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • blurred vision, or seeing halos around lights;




  • uneven heartbeats;




  • sleep problems (insomnia);




  • ongoing headache;




  • weight gain, puffiness in your face;




  • increased thirst or urination, weight loss, unusual weakness;




  • fever, sore throat, tired feeling;




  • severe pain, burning, or irritation of treated skin;




  • rectal bleeding;




  • any new redness or swelling where the medicine was applied; or




  • itching, oozing, or other signs of infection.



Less serious side effects may include:



  • mild skin redness, burning, itching, dryness, or peeling;




  • acne;




  • changes in the color of treated skin;




  • thinning of your skin;




  • blistering skin; or




  • stretch marks.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Proctocream HC (hydrocortisone and pramoxine topical)?


It is not likely that other drugs you take orally or inject will have an effect on topically applied hydrocortisone and pramoxine. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Proctocream HC resources


  • Proctocream HC Side Effects (in more detail)
  • Proctocream HC Use in Pregnancy & Breastfeeding
  • Proctocream HC Drug Interactions
  • Proctocream HC Support Group
  • 16 Reviews for Proctocream HC - Add your own review/rating


  • Proctocream HC Prescribing Information (FDA)

  • Analpram-HC Cream MedFacts Consumer Leaflet (Wolters Kluwer)

  • Epifoam Foam MedFacts Consumer Leaflet (Wolters Kluwer)

  • Epifoam Prescribing Information (FDA)

  • Novacort MedFacts Consumer Leaflet (Wolters Kluwer)

  • Pramosone Prescribing Information (FDA)

  • Pramosone Lotion MedFacts Consumer Leaflet (Wolters Kluwer)

  • Proctofoam HC Prescribing Information (FDA)

  • Proctofoam HC Foam MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Proctocream HC with other medications


  • Dermatitis
  • Dermatological Disorders
  • Hemorrhoids
  • Psoriasis


Where can I get more information?


  • Your pharmacist can provide more information about hydrocortisone and pramoxine topical.

See also: Proctocream HC side effects (in more detail)


Plan B One-Step Oral


Generic Name: levonorgestrel (Oral route)

lee-voe-nor-JES-trel

Commonly used brand name(s)

In the U.S.


  • Next Choice

  • Plan B

  • Plan B One-Step

Available Dosage Forms:


  • Tablet

Therapeutic Class: Contraceptive, Progestin


Pharmacologic Class: Progestin


Uses For Plan B One-Step


Levonorgestrel is an emergency contraceptive that is used to prevent pregnancy after unprotected sex or after failure of another birth control method. It works by preventing a woman's egg from fully developing. It may also prevent the attachment of the woman's egg to the wall of the uterus (womb).


No contraceptive method is 100 percent effective. Birth control methods such as having surgery to become sterile or not having sex are more effective. This medicine should not be used as a regular method of birth control. Discuss with your doctor your options for birth control.


This medicine is available only under a special distribution program called Convenient Access, Responsible Education (CARE) program.


Before Using Plan B One-Step


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of levonorgestrel in teenage females. This medicine may be used for birth control in teenage females but is not recommended before the start of menstruation.


Geriatric


Appropriate studies on the relationship of age to the effects of levonorgestrel have not been performed in the geriatric population. This medicine is not indicated for use in elderly women.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersXStudies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Isotretinoin

  • Theophylline

  • Tizanidine

  • Tranexamic Acid

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acitretin

  • Alprazolam

  • Amoxicillin

  • Ampicillin

  • Amprenavir

  • Aprepitant

  • Atazanavir

  • Bacampicillin

  • Betamethasone

  • Bexarotene

  • Bosentan

  • Carbamazepine

  • Colesevelam

  • Cyclosporine

  • Darunavir

  • Delavirdine

  • Doxycycline

  • Efavirenz

  • Etravirine

  • Fosamprenavir

  • Fosaprepitant

  • Fosphenytoin

  • Griseofulvin

  • Lamotrigine

  • Licorice

  • Minocycline

  • Modafinil

  • Mycophenolate Mofetil

  • Mycophenolic Acid

  • Nelfinavir

  • Nevirapine

  • Oxcarbazepine

  • Oxytetracycline

  • Phenobarbital

  • Phenytoin

  • Pioglitazone

  • Prednisolone

  • Primidone

  • Rifabutin

  • Rifampin

  • Rifapentine

  • Ritonavir

  • Rosuvastatin

  • Rufinamide

  • Selegiline

  • St John's Wort

  • Tacrine

  • Telaprevir

  • Tetracycline

  • Topiramate

  • Troglitazone

  • Troleandomycin

  • Voriconazole

  • Warfarin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.


  • Caffeine

Proper Use of levonorgestrel

This section provides information on the proper use of a number of products that contain levonorgestrel. It may not be specific to Plan B One-Step. Please read with care.


To make using emergency contraceptives as safe and reliable as possible, you should understand how and when to use them and what effects may be expected.


This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.


Plan B® and Plan B® One-Step is available as an over-the-counter medicine for women 17 years of age and older, and is available only with a doctor's prescription for women younger than 17 years of age.


Use this medicine exactly as directed by your doctor. This medicine is for occasional use as an emergency birth control. It should not replace your regular birth control method. You may use this medicine at any time during your monthly period.


If you vomit within 2 hours of taking this medicine, call your doctor right away. Your doctor may prescribe another tablet for you.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For emergency contraception:
    • For oral dosage form (Plan B® One-Step tablets):
      • Adults and teenagers 17 years of age and older—One tablet taken as soon as possible not more than 72 hours (3 days) after unprotected sex or after failure of another birth control method.

      • Children younger than 17 years of age—Use and dose must be determined by your doctor.


    • For oral dosage form (Plan B® tablets):
      • Adults and teenagers 17 years of age and older—One tablet taken as soon as possible not more than 72 hours (3 days) after unprotected sex or after failure of another birth control method. A second tablet should be taken 12 hours after the first dose.

      • Children younger than 17 years of age—Use and dose must be determined by your doctor.



Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Plan B One-Step


It is very important that your doctor check you closely to make sure this medicine is working properly and does not cause unwanted effects.


Although you are using this medicine to prevent pregnancy, you should know that using this medicine while you are pregnant could harm the unborn baby. Your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.


Call your doctor right away if you have severe lower abdominal or stomach pain 3 to 5 weeks after taking this medicine. You may have a pregnancy outside of the uterus (womb), which is called an ectopic pregnancy. An ectopic pregnancy can be a serious and life-threatening condition. It can also cause problems that may make it harder for you to become pregnant in the future.


You may have some blood spotting a few days after taking this medicine. If the bleeding continues for more than 1 week, check with your doctor right away.


This medicine may make your next monthly period later than expected by a few days. If your next period after taking this medicine is more than 1 week late, check with your doctor right away for a pregnancy test.


This medicine will not protect you from getting HIV/AIDS or other sexually transmitted infections. If this is a concern for you, talk with your doctor.


Your regular birth control method such as birth control pills or patch may not work as well while you are using this medicine. After using this medicine, you must use two forms of birth control. Use birth control pills or patch together with another form of birth control, such as a condom, diaphragm, or contraceptive foam or jelly, during any other times that you have sex in the same monthly period you used this medicine.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (e.g., St. John's wort) or vitamin supplements.


Plan B One-Step Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Heavy or light menstrual bleeding

Incidence not known
  • Absent missed or irregular menstrual periods

  • cramps

  • irregular menstruation

  • pain

  • pain in the pelvis

  • stopping of menstrual bleeding

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Abdominal or stomach pain

  • dizziness

  • headache

  • nausea

  • tenderness of the breasts

  • unusual tiredness or weakness

  • vomiting

Less common
  • Diarrhea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Plan B One-Step Oral side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Plan B One-Step Oral resources


  • Plan B One-Step Oral Side Effects (in more detail)
  • Plan B One-Step Oral Use in Pregnancy & Breastfeeding
  • Drug Images
  • Plan B One-Step Oral Drug Interactions
  • 14 Reviews for Plan B One-Step Oral - Add your own review/rating


Compare Plan B One-Step Oral with other medications


  • Emergency Contraception

Phenylephrine/Potassium Guaiacolsulfonate Liquid


Pronunciation: fen-ill-EF-rin/poe-TASS-ee-uhm gwie-ah-kole-SULL-foe-nate
Generic Name: Phenylephrine/Potassium Guaiacolsulfonate
Brand Name: KGS-PE


Phenylephrine/Potassium Guaiacolsulfonate Liquid is used for:

Relieving symptoms of congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.


Phenylephrine/Potassium Guaiacolsulfonate Liquid is a decongestant and expectorant combination. It works by constricting blood vessels and shrinking swollen and congested nasal tissues (mucous membranes) and by thinning and loosening mucus in the airway. This allows you to breathe more easily and makes coughs more productive.


Do NOT use Phenylephrine/Potassium Guaiacolsulfonate Liquid if:


  • you are allergic to any ingredient in Phenylephrine/Potassium Guaiacolsulfonate Liquid

  • you have severe high blood pressure, severe heart blood vessel disease, a rapid heartbeat, or severe heart problems

  • you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Phenylephrine/Potassium Guaiacolsulfonate Liquid:


Some medical conditions may interact with Phenylephrine/Potassium Guaiacolsulfonate Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat

  • if you have a history of adrenal gland problems (eg, tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, an enlarged prostate or other prostate problems, seizures, or an overactive thyroid

  • if you have chronic cough

Some MEDICINES MAY INTERACT with Phenylephrine/Potassium Guaiacolsulfonate Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects of Phenylephrine/Potassium Guaiacolsulfonate Liquid may be increased

  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased

  • Bromocriptine because side effects may be increased by Phenylephrine/Potassium Guaiacolsulfonate Liquid

  • Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased by Phenylephrine/Potassium Guaiacolsulfonate Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Phenylephrine/Potassium Guaiacolsulfonate Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Phenylephrine/Potassium Guaiacolsulfonate Liquid:


Use Phenylephrine/Potassium Guaiacolsulfonate Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Phenylephrine/Potassium Guaiacolsulfonate Liquid may be taken with or without food.

  • Take Phenylephrine/Potassium Guaiacolsulfonate Liquid with a full glass of water unless your doctor directs otherwise.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of Phenylephrine/Potassium Guaiacolsulfonate Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Phenylephrine/Potassium Guaiacolsulfonate Liquid.



Important safety information:


  • Phenylephrine/Potassium Guaiacolsulfonate Liquid may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Phenylephrine/Potassium Guaiacolsulfonate Liquid. Using Phenylephrine/Potassium Guaiacolsulfonate Liquid alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do not take diet or appetite control medicines while you are taking Phenylephrine/Potassium Guaiacolsulfonate Liquid without checking with you doctor.

  • Do NOT exceed the recommended dose or use/take Phenylephrine/Potassium Guaiacolsulfonate Liquid for longer than prescribed without checking with your doctor.

  • Phenylephrine/Potassium Guaiacolsulfonate Liquid contains phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Phenylephrine/Potassium Guaiacolsulfonate Liquid may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking Phenylephrine/Potassium Guaiacolsulfonate Liquid.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Phenylephrine/Potassium Guaiacolsulfonate Liquid.

  • Use Phenylephrine/Potassium Guaiacolsulfonate Liquid with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Phenylephrine/Potassium Guaiacolsulfonate Liquid in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Phenylephrine/Potassium Guaiacolsulfonate Liquid, discuss with your doctor the benefits and risks of using Phenylephrine/Potassium Guaiacolsulfonate Liquid during pregnancy. It is unknown if Phenylephrine/Potassium Guaiacolsulfonate Liquid is excreted in breast milk. Do not breast-feed while taking Phenylephrine/Potassium Guaiacolsulfonate Liquid.


Possible side effects of Phenylephrine/Potassium Guaiacolsulfonate Liquid:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Phenylephrine/Potassium Guaiacolsulfonate side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of Phenylephrine/Potassium Guaiacolsulfonate Liquid:

Store Phenylephrine/Potassium Guaiacolsulfonate Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Phenylephrine/Potassium Guaiacolsulfonate Liquid out of the reach of children and away from pets.


General information:


  • If you have any questions about Phenylephrine/Potassium Guaiacolsulfonate Liquid, please talk with your doctor, pharmacist, or other health care provider.

  • Phenylephrine/Potassium Guaiacolsulfonate Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Phenylephrine/Potassium Guaiacolsulfonate Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Phenylephrine/Potassium Guaiacolsulfonate resources


  • Phenylephrine/Potassium Guaiacolsulfonate Side Effects (in more detail)
  • Phenylephrine/Potassium Guaiacolsulfonate Use in Pregnancy & Breastfeeding
  • Phenylephrine/Potassium Guaiacolsulfonate Drug Interactions
  • Phenylephrine/Potassium Guaiacolsulfonate Support Group
  • 0 Reviews · Be the first to review/rate this drug

Patanol



Generic Name: Olopatadine Hydrochloride
Class: Antiallergic Agents
ATC Class: S01GX09
VA Class: OP900
Chemical Name: 11-[(Z)-3-(dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride
Molecular Formula: C21H23NO3•HCl
CAS Number: 140462-76-6

Introduction

Relatively selective histamine H1-receptor antagonist1 2 3 4 5 6 and mast-cell stabilizer.1 2 3 4 5 6 b


Uses for Patanol


Allergic Conjunctivitis


Temporary prevention of ocular itching associated with allergic conjunctivitis.1 2 13


Patanol Dosage and Administration


Administration


Ophthalmic Administration


Apply topically to the eye as an ophthalmic solution.1 Not for injection or oral use.1


If more than one topical ophthalmic drug is used, administer the drugs at least 5 minutes apart.12


Avoid contamination of the solution container.1


Dosage


Available as olopatadine hydrochloride; dosage expressed in terms of olopatadine.1


Pediatric Patients


Allergic Conjunctivitis

Ophthalmic

Children ≥3 years of age: 1 or 2 drops of a 0.1% solution in the affected eye(s) twice daily (at an interval of 6–8 hours).1


Once symptomatic improvement is established, continue therapy for as long as necessary to sustain improvement.12


Adults


Allergic Conjunctivitis

Ophthalmic

1 or 2 drops of a 0.1% solution in the affected eye(s) twice daily (at an interval of 6–8 hours).1


Once symptomatic improvement is established, continue therapy for as long as necessary to sustain improvement.12


Cautions for Patanol


Contraindications



  • Known hypersensitivity to olopatadine or any ingredient in the formulation.1



Warnings/Precautions


Specific Populations


Pregnancy

Category C.1


Lactation

Distributed into milk in rats following oral administration;1 not known whether distributed into human milk following topical application to the eye.1 Use with caution.1


Pediatric Use

Safety and efficacy not established in children <3 years of age.1


Appears to be well-tolerated in children 3–16 years of age.11 13


Geriatric Use

No substantial differences in safety and efficacy relative to younger adults.a


Common Adverse Effects


Headache.1 2 13


Interactions for Patanol


No formal drug interaction studies to date.12


Patanol Pharmacokinetics


Absorption


Bioavailability


Limited systemic exposure following topical application to the eye;1 plasma concentrations usually are undetectable.1 12 13


Onset


Rapid onset;3 13 14 15 symptomatic relief of itching generally occurs within 30 minutes.12 13 15


Duration


Long duration (≥8 hours).3 13 14 15


Distribution


Extent


Distribution into human ocular tissues and fluids not characterized.1


Elimination


Metabolism


Metabolized in the liver to monodesmethyl olopatadine and olopatadine N-oxide following topical application to the eyes.1 12


Elimination Route


Eliminated principally by renal excretion; 60–70% of systemically absorbed dose excreted in urine as parent drug.1 12


Half-life


Approximately 3 hours following topical application to the eyes.1


Stability


Storage


Ophthalmic


Solution

4–25°C.1


ActionsActions



  • Inhibits type I immediate hypersensitivity reactions in vitro and in vivo.1 3




  • Suppresses the release of inflammatory mediators (e.g., histamine, prostaglandin D2, tryptase) in response to antigenic stimulation of human conjunctival mast cells in a dose-dependent manner.5 13




  • Inhibits histamine-stimulated conjunctival vascular permeability response in a concentration-dependent manner.3




  • Potency is comparable to that of levocabastine and exceeds that of pheniramine or antazoline.3 13



Advice to Patients



  • Importance of learning and adhering to proper administration techniques to avoid contamination of the solution container.1 12




  • Importance of removing soft contact lenses prior to administration of each dose.1 Delay reinsertion for 10 minutes after administration if eyes are not red; do not wear contact lenses if eye(s) are red.1 12 Not indicated for contact lens-related irritation.1




  • Importance of administering different topical ophthalmic preparations at least 5 minutes apart.12




  • Importance of patients informing clinicians of exisiting or contemplated therapy, including prescription and OTC drugs.




  • Importance of women informing clinicians if they are or plan to become pregnant or to breast-feed.a




  • Importance of informing patients of other important precautionary information.a (See Cautions.)



Preparations


Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.













Olopatadine Hydrochloride

Routes



Dosage Forms



Strengths



Brand Names



Manufacturer



Ophthalmic



Solution



0.1% (of olopatadine)



Patanol (with benzalkonium chloride)



Alcon


Comparative Pricing


This pricing information is subject to change at the sole discretion of DS Pharmacy. This pricing information was updated 03/2011. Actual costs to patients will vary depending on the use of specific retail or mail-order locations and health insurance copays.


Pataday 0.2% Solution (ALCON VISION): 2/$119.99 or 7/$334.98


Patanol 0.1% Solution (ALCON VISION): 5/$125.99 or 15/$359.99



Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.


The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions May 2004. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.




References



1. Alcon Laboratories. Patanol (olopatadine hydrochloride) ophthalmic solution 0.1% prescribing information. Fort Worth, TX; 1996 Dec.



2. Anon. Olopatadine for allergic conjunctivitis. Med Lett Drugs Ther. 1997; 39:108-9. [PubMed 9398823]



3. Yanni JM, Stephens DJ, Miller ST et al. The in vitro and in vivo ocular pharmacology of olopatadine (AL-4943A), an effective anti-allergic/antihistaminic agent. J Ocul Pharmacol Ther. 1996; 12:389-400. [PubMed 8951675]



4. Sharif NA, Xu SX, Yanni JM. Olopatadine (AL-4943A): ligand binding and functional studies on a novel, long acting H1-selective histamine antagonist and anti-allergic agent for use in allergic conjunctivitis. J Ocul Pharmacol Ther. 1996; 12:401-7. [PubMed 8951676]



5. Sharif NA, Xu SX, Miller ST et al. Characterization of the ocular antiallergic and antihistaminic effects of olopatadine (AL-4943A), a novel drug for treating ocular allergic diseases. J Pharmacol Exp Ther. 1996; 278:1252-61. [PubMed 8819509]



6. Kamei C, Sugimoto Y, Nakamura S et al. Effect of (Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride on experimental allergic conjunctivitis and rhinitis in rats and guinea pigs. Arzneimittelforschung. 1995; 45:1005-8. [PubMed 7488300]



7. Ciprandi G, Buscaglia S, Cerqueti PM et al. Drug treatment of allergic conjunctivitis: a review of the evidence. Drugs. 1992; 43:154-76. [IDIS 360840] [PubMed 1372215]



8. Morrow GL, Abbott RL. Conjunctivitis. Am Fam Physician. 1998; 57:735-46. [IDIS 418448] [PubMed 9490996]



9. Titi MJ. A critical look at ocular allergy drugs. Am Fam Physician. 1996; 53:2637-42. [IDIS 367250] [PubMed 8644576]



10. Galindez OA, Kaufman HE. Coping with the itchy-burnies: the management of allergic conjunctivitis. Ophthalmology. 1996; 103:1335-6. [IDIS 373485] [PubMed 8841290]



11. Reviewers’ comments (personal observations).



12. Alcon Laboratories; Fort Worth, TX: Personal communication.



13. Alcon Laboratories. Patanol (olopatadine hydrochloride) ophthalmic solution 0.1% product monograph. Fort Worth, TX: (not dated).



14. Abelson MB, Spitalny L. Combined analysis of two studies using the conjunctival allergen challenge model to evaluate olopatadine hydrochloride, a new ophthalmic antiallergic agent with dual activity. Am J Ophthalmol. 1998; 125:797-804. [IDIS 409293] [PubMed 9645717]



15. Abelson MB. Evaluation of olopatadine, a new ophthalmic antiallergic agent with dual activity, using the conjunctival allergen challenge model. Ann Allergy Asthma Immunol. 1998; 81:211-8. [IDIS 415165] [PubMed 9759796]



a. Alcon Laboratories. Patanol (olopatadine hydrochloride) ophthalmic solution 0.1% prescribing information. Fort Worth, TX; 2003 Dec.



b. Anon. New drugs for allergic conjunctivitis. Med Lett Drugs Ther. 2000; 42:39-40. [PubMed 10825920]



More Patanol resources


  • Patanol Side Effects (in more detail)
  • Patanol Use in Pregnancy & Breastfeeding
  • Patanol Support Group
  • 8 Reviews for Patanol - Add your own review/rating


  • Patanol Prescribing Information (FDA)

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  • Seasonal Allergic Conjunctivitis

Panixine DisperDose



Generic Name: cephalexin (Oral route)

sef-a-LEX-in

Commonly used brand name(s)

In the U.S.


  • Bio-Cef

  • Keflex

  • Panixine DisperDose

In Canada


  • Novo-Lexin

Available Dosage Forms:


  • Tablet

  • Capsule

  • Tablet for Suspension

  • Powder for Suspension

Therapeutic Class: Antibiotic


Pharmacologic Class: 1st Generation Cephalosporin


Uses For Panixine DisperDose


Cephalexin is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.


This medicine is available only with your doctor's prescription.


Before Using Panixine DisperDose


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of cephalexin in children.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cephalexin in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cephalexin.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Cholestyramine

  • Metformin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Colitis (inflammation in gut), history of or

  • Diarrhea, severe, history of—Use with caution. May make these conditions worse.

  • Kidney disease—Use with caution. Effects may be increased because of slower removal of the medicine from the body.

Proper Use of cephalexin

This section provides information on the proper use of a number of products that contain cephalexin. It may not be specific to Panixine DisperDose. Please read with care.


Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.


Shake the oral liquid well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.


Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage forms (capsules or suspension):
    • For infections:
      • Adults and teenagers—The dose is 1000 to 4000 milligrams (mg) per day, taken in divided doses.

      • Children—Use and dose must be determined by your doctor. Dose is based on body weight and must be determined by your doctor. The dose is usually 25 to 100 milligrams (mg) per kilogram (kg) per day, taken in divided doses.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Store the capsules in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days.


Precautions While Using Panixine DisperDose


If your symptoms do not improve within a few days, or if they become worse, check with your doctor.


Cephalexin may cause diarrhea, and in some cases it can be severe. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.


Before you or your child have any medical tests, tell the medical doctor in charge that you are using this medicine. The results of some tests may be affected by this medicine.


Panixine DisperDose Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Diarrhea

Rare
  • Abdominal or stomach pain

  • blistering, peeling, or loosening of the skin

  • chills

  • clay-colored stools

  • cough

  • dark urine

  • diarrhea

  • dizziness

  • fever

  • general tiredness and weakness

  • headache

  • itching

  • joint or muscle pain

  • light-colored stools

  • loss of appetite

  • nausea and vomiting

  • rash

  • red skin lesions, often with a purple center

  • red, irritated eyes

  • sore throat

  • sores, ulcers, or white spots in the mouth or on the lips

  • unpleasant breath odor

  • unusual tiredness or weakness

  • upper right abdominal or stomach pain

  • vomiting of blood

  • yellow eyes or skin

Incidence not known
  • Abdominal or stomach cramps or tenderness

  • back or leg pains

  • black, tarry stools

  • bleeding gums

  • bloating

  • blood in the urine or stools

  • chest pain

  • coughing up blood

  • diarrhea, watery and severe, which may also be bloody

  • difficulty with breathing or swallowing

  • fast heartbeat

  • general body swelling

  • hives

  • increased menstrual flow or vaginal bleeding

  • increased thirst

  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

  • loss of appetite

  • nosebleeds

  • pain

  • painful or difficult urination

  • pale skin

  • paralysis

  • pinpoint red spots on the skin

  • prolonged bleeding from cuts

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • red or black, tarry stools

  • red or dark brown urine

  • shortness of breath

  • swollen or painful glands

  • tightness in the chest

  • unusual bleeding or bruising

  • unusual weight loss

  • watery or bloody diarrhea

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Incidence not known
  • Acid or sour stomach

  • anxiety

  • belching

  • burning feeling in the chest or stomach

  • difficulty with moving

  • dry mouth

  • heartburn

  • hives or welts

  • hyperventilation

  • indigestion

  • irregular heartbeats

  • irritability

  • itching of the vagina or genital area

  • muscle pain or stiffness

  • nervousness

  • pain during sexual intercourse

  • pain, swelling, or redness in the joints

  • redness of the skin

  • restlessness

  • seeing, hearing, or feeling things that are not there

  • shaking

  • stomach upset

  • trouble with sleeping

  • white or brownish vaginal discharge

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Panixine DisperDose side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


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Patanol Drops



Pronunciation: oh-loe-pa-TA-deen
Generic Name: Olopatadine
Brand Name: Examples include Pataday and Patanol


Patanol Drops are used for:

Preventing itchy, red, or watery eyes due to allergies (eg, pollen, pollution, dust, animal dander). Patanol Drops may be used alone or with other allergy medicines.


Patanol Drops are an antihistamine. It works by blocking the action of histamine, which reduces the eye symptoms of an allergic reaction (eg, itchy, red, watery).


Do NOT use Patanol Drops if:


  • you are allergic to any ingredient in Patanol Drops

Contact your doctor or health care provider right away if any of these apply to you.



Before using Patanol Drops:


Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you wear contact lenses

Some MEDICINES MAY INTERACT with Patanol Drops. However, no specific interactions with Patanol Drops are known at this time.


Ask your health care provider if Patanol Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Patanol Drops:


Use Patanol Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Patanol Drops are only for the eye. Do not get it in your nose or mouth.

  • Do NOT use Patanol Drops in your eyes while you are wearing contact lenses. Soft contact lenses may absorb a chemical in Patanol Drops; wait 10 minutes after you use Patanol Drops before you put your contacts back in. Only reinsert your contact lenses if your eyes are not red.

  • To use Patanol Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.

  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.

  • Patanol Drops works best when used regularly, before signs and symptoms begin to occur. If your symptoms continue, contact your health care provider. Do not use Patanol Drops for a longer period of time than your health care provider prescribed it for.

  • If you miss a dose of Patanol Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Patanol Drops.



Important safety information:


  • Do not use Patanol Drops to treat contact lens irritation. Redness due to contact lens wear may not be caused by allergies. Do not wear contact lenses if your eyes are red. If redness continues, talk to your health care provider.

  • Do not use Patanol Drops for future eye problems without first checking with your health care provider.

  • Patanol Drops should not be used in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Patanol Drops while you are pregnant. It is not known if Patanol Drops are found in breast milk. If you are or will be breast-feeding while you use Patanol Drops, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Patanol Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Blurred vision; burning or stinging; change in taste; dryness of the eye; eye pain; feeling that something is in your eye; head congestion; headache; itching; redness in the eye; runny nose; sore throat; tearing; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Patanol side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Patanol Drops may be harmful if swallowed.


Proper storage of Patanol Drops:

Store Patanol Drops between 39 and 77 degrees F (4 and 25 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Patanol Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Patanol Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Patanol Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Patanol Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Patanol resources


  • Patanol Side Effects (in more detail)
  • Patanol Dosage
  • Patanol Use in Pregnancy & Breastfeeding
  • Patanol Support Group
  • 8 Reviews for Patanol - Add your own review/rating


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